Mechanical Engineering and Metalworking Industry in Latvia

72.19 Other research and experimental development on natural sciences and engineering

Enterprise Europe Network (Profile: TRES20200313001)

Short description of advertisement: 
Spanish company is looking for medical device manufacturers for a new endouterine biosensor to control and stimulate human fertility

A Spanish SME working in the clinical consulting field has patented a new endouterine biosensor aimed at facilitating the crossing of sperm through the cervical mucus and detecting the presence of sperm in the cervical canal towards the uterine cavity in vivo. This device is especially addressed to subfertility cases with a previous diagnosis of low sperm motility. They look for manufacturers of medical devices interested in technical cooperation agreements.

A Spanish SME with wide expertise in functional reproductive medicine and biotechnology has developed a new endouterine biosensor aimed at facilitating the sperm to get through the cervical mucus to fertilize a woman’s egg and monitoring the sperm ascent in vivo.

Around 60 to 80 million couples worldwide are affected by infertility, and the rates vary from country to country. In the United States, for instance, the rate is around 10 per cent of couples. Male factor infertility accounts for between 40 to 50 per cent of infertility cases and affects around 7 per cent of men. Many of these cases are caused by low sperm motility. This is important in fertility because sperm needs to move through the woman’s reproductive tract to reach and fertilize her egg.

The purpose of this device is mainly to let the sperm swim through the cervical mucus, and detect the presence of sperm in the intracervical ascent channel towards the uterine cavity. This device uses as biological material the cervical mucus.

The modular device presents, at the level of the side walls, permeable cells arranged regularly, one after the other, distributed in the way of circumference, along the flexible tube in such a way that the liquid fluid can pass freely. Inside, the micro tubule complex has a tray-shaped micro-channel system for receiving cervical mucus. In the outer part of the wall of the circumference of the module, in contact with the side walls of the micro channels, it has a peripheral system of sensors. This system is in contact with the cervical fluid and allows recording the sperm ascent.

It is a novel idea alternative to artificial techniques, capable of being sensitive to the movement of sperm in its natural fluid and allows storing and collecting a fluid sample "liquid biopsy" for study and analysis .

The invention has the following advantages:

  • It is an alternative to artificial reproduction techniques and artificial techniques for sperm capacitation.
  • It provides additional and more valuable information than traditional techniques.
  • It has an integrated modular system of easy placement and extraction for analysis and post-processing of data.
  • It is applicable to fertility recognition programs currently recognized worldwide by the scientific community.

The company is looking for an industrial partner in order to develop, with their assistance and under a technical cooperation agreement, a medical commercial device with the technical specifications provided.



For more information please contact Enterprise Europe Network Latvia.

Contact person: 
Enterprise Europe Network Latvia
Contact languages: 
Perses Street 2, Riga, LV-1442, Latvia
info [at] een [dot] lv
Proposal valid till: 
Sunday, 14 March, 2021


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